Inhibition of K(Ca)2 and K(v)11.1 Channels in Pigs With Left Ventricular Dysfunction

BACKGROUND: Inhibition of K(Ca)2 channels, conducting I(KCa), can convert atrial fibrillation (AF) to sinus rhythm and protect against its induction. I(KCa) inhibition has been shown to possess functional atrial selectivity with minor effects on ventricles. Under pathophysiological conditions with v...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Citerni, Carlotta, Kirchhoff, Jeppe, Olsen, Lisbeth Høier, Sattler, Stefan Michael, Grunnet, Morten, Edvardsson, Nils, Bentzen, Bo Hjorth, Diness, Jonas Goldin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219273/
https://ncbi.nlm.nih.gov/pubmed/32435191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00556
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