Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Due to their bacterial ancestry, many components of mitochondria share structural similarities with bacteria. Release of molecular danger signals from injured cell mitochondria (mitochondria-derived damage-associated molecular patterns, mito-DAMPs) triggers a potent inflammatory response, but their...

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Publicado no:Nat Commun
Main Authors: An, Ping, Wei, Lin-Lin, Zhao, Shuangshuang, Sverdlov, Deanna Y., Vaid, Kahini A., Miyamoto, Makoto, Kuramitsu, Kaori, Lai, Michelle, Popov, Yury V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217909/
https://ncbi.nlm.nih.gov/pubmed/32398673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16092-0
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