Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Due to their bacterial ancestry, many components of mitochondria share structural similarities with bacteria. Release of molecular danger signals from injured cell mitochondria (mitochondria-derived damage-associated molecular patterns, mito-DAMPs) triggers a potent inflammatory response, but their...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: An, Ping, Wei, Lin-Lin, Zhao, Shuangshuang, Sverdlov, Deanna Y., Vaid, Kahini A., Miyamoto, Makoto, Kuramitsu, Kaori, Lai, Michelle, Popov, Yury V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217909/
https://ncbi.nlm.nih.gov/pubmed/32398673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16092-0
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