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The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis

The pathogenesis of primary sclerosing cholangitis (PSC) and the mechanistic link to inflammatory bowel disease remain ill‐defined. Ectonucleoside triphosphate diphosphohydrolase‐1 (ENTPD1)/clusters of differentiation (CD) 39, the dominant purinergic ecto‐enzyme, modulates intestinal inflammation. H...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Peng, Zhen‐Wei, Rothweiler, Sonja, Wei, Guangyan, Ikenaga, Naoki, Liu, Susan B., Sverdlov, Deanna Y., Vaid, Kahini A., Longhi, Maria Serena, Kuang, Ming, Robson, Simon C., Popov, Yury V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721459/
https://ncbi.nlm.nih.gov/pubmed/29404503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1084
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