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Ensembles of Hydrophobicity Scales as Potent Classifiers for Chimeric Virus-Like Particle Solubility – An Amino Acid Sequence-Based Machine Learning Approach

Virus-like particles (VLPs) are protein-based nanoscale structures that show high potential as immunotherapeutics or cargo delivery vehicles. Chimeric VLPs are decorated with foreign peptides resulting in structures that confer immune responses against the displayed epitope. However, insertion of fo...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Vormittag, Philipp, Klamp, Thorsten, Hubbuch, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217080/
https://ncbi.nlm.nih.gov/pubmed/32432098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00395
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