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Process monitoring of virus‐like particle reassembly by diafiltration with UV/Vis spectroscopy and light scattering
Virus‐like particles (VLPs) have shown great potential as biopharmaceuticals in the market and in clinics. Nonenveloped, in vivo assembled VLPs are typically disassembled and reassembled in vitro to improve particle stability, homogeneity, and immunogenicity. At the industrial scale, cross‐flow filt...
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| 出版年: | Biotechnol Bioeng |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6593973/ https://ncbi.nlm.nih.gov/pubmed/30684365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26935 |
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