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Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration

Virus-like particles (VLPs) are emerging nanoscale protein assemblies applied as prophylactic vaccines and in development as therapeutic vaccines or cargo delivery systems. Downstream processing (DSP) of VLPs comes both with challenges and opportunities, depending on the complexity and size of the s...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Hillebrandt, Nils, Vormittag, Philipp, Bluthardt, Nicolai, Dietrich, Annabelle, Hubbuch, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326125/
https://ncbi.nlm.nih.gov/pubmed/32671023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00489
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