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Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration

Virus-like particles (VLPs) are emerging nanoscale protein assemblies applied as prophylactic vaccines and in development as therapeutic vaccines or cargo delivery systems. Downstream processing (DSP) of VLPs comes both with challenges and opportunities, depending on the complexity and size of the s...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Hillebrandt, Nils, Vormittag, Philipp, Bluthardt, Nicolai, Dietrich, Annabelle, Hubbuch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326125/
https://ncbi.nlm.nih.gov/pubmed/32671023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00489
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