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Ensembles of Hydrophobicity Scales as Potent Classifiers for Chimeric Virus-Like Particle Solubility – An Amino Acid Sequence-Based Machine Learning Approach

Virus-like particles (VLPs) are protein-based nanoscale structures that show high potential as immunotherapeutics or cargo delivery vehicles. Chimeric VLPs are decorated with foreign peptides resulting in structures that confer immune responses against the displayed epitope. However, insertion of fo...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Vormittag, Philipp, Klamp, Thorsten, Hubbuch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217080/
https://ncbi.nlm.nih.gov/pubmed/32432098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00395
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