Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC: ALK- and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition

Anaplastic lymphoma-kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is prone to developing heterogeneous, only partly known mechanisms of resistance to ALK-tyrosine-kinase-inhibitors (ALK-TKIs). We present a case of a 38-year old male, who never smoked with disseminated ALK-rearranged (EM...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Urbanska, Edyta M., Sørensen, Jens B., Melchior, Linea C., Costa, Junia C., Santoni-Rugiu, Eric
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Case Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215933/
https://ncbi.nlm.nih.gov/pubmed/32325863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082847
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires