Donor CYP3A5 Gene Polymorphism Alone Cannot Predict Tacrolimus Intrarenal Concentration in Renal Transplant Recipients

CYP3A5 gene polymorphism in recipients plays an important role in tacrolimus blood pharmacokinetics after renal transplantation. Even though CYP3A5 protein is expressed in renal tubular cells, little is known about the influence on the tacrolimus intrarenal exposure and hence graft outcome. The aim...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Zhang, Mengyu, Tajima, Soichiro, Shigematsu, Tomohiro, Fu, Rao, Noguchi, Hiroshi, Kaku, Keizo, Tsuchimoto, Akihiro, Okabe, Yasuhiro, Egashira, Nobuaki, Masuda, Satohiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215698/
https://ncbi.nlm.nih.gov/pubmed/32340188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082976
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