Donor CYP3A5 Gene Polymorphism Alone Cannot Predict Tacrolimus Intrarenal Concentration in Renal Transplant Recipients

CYP3A5 gene polymorphism in recipients plays an important role in tacrolimus blood pharmacokinetics after renal transplantation. Even though CYP3A5 protein is expressed in renal tubular cells, little is known about the influence on the tacrolimus intrarenal exposure and hence graft outcome. The aim...

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Udgivet i:Int J Mol Sci
Main Authors: Zhang, Mengyu, Tajima, Soichiro, Shigematsu, Tomohiro, Fu, Rao, Noguchi, Hiroshi, Kaku, Keizo, Tsuchimoto, Akihiro, Okabe, Yasuhiro, Egashira, Nobuaki, Masuda, Satohiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215698/
https://ncbi.nlm.nih.gov/pubmed/32340188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082976
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