Donor CYP3A5 Gene Polymorphism Alone Cannot Predict Tacrolimus Intrarenal Concentration in Renal Transplant Recipients

CYP3A5 gene polymorphism in recipients plays an important role in tacrolimus blood pharmacokinetics after renal transplantation. Even though CYP3A5 protein is expressed in renal tubular cells, little is known about the influence on the tacrolimus intrarenal exposure and hence graft outcome. The aim...

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Publicado en:Int J Mol Sci
Autores principales: Zhang, Mengyu, Tajima, Soichiro, Shigematsu, Tomohiro, Fu, Rao, Noguchi, Hiroshi, Kaku, Keizo, Tsuchimoto, Akihiro, Okabe, Yasuhiro, Egashira, Nobuaki, Masuda, Satohiro
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215698/
https://ncbi.nlm.nih.gov/pubmed/32340188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082976
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