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Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 Downregulation

Due to a superior dose conformity to the target, proton beam therapy (PBT) continues to rise in popularity. Recently, considerable efforts have been directed toward discovering treatment options for use in combination with PBT. This study aimed to investigate the targeting of checkpoint kinase 1 (CH...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Choi, Changhoon, Cho, Won Kyung, Park, Sohee, Shin, Sung-Won, Park, Won, Kim, Haeyoung, Choi, Doo Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215565/
https://ncbi.nlm.nih.gov/pubmed/32294924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082691
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