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Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.
Eukaryotic cells respond to DNA damage and S phase replication blocks by arresting cell-cycle progression through the DNA structure checkpoint pathways. In Schizosaccharomyces pombe, the Chk1 kinase is essential for mitotic arrest and is phosphorylated after DNA damage. During S phase, the Cds1 kina...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1998
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171070/ https://ncbi.nlm.nih.gov/pubmed/9857181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.24.7239 |
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