Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

Genome integrity is monitored by a checkpoint that delays mitosis in response to DNA damage. This checkpoint is enforced by Chk1, a protein kinase that inhibits the mitotic inducer Cdc25. In fission yeast, Chk1 is regulated by a group of proteins that includes Rad3, a protein kinase related to human...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lopez-Girona, Antonia, Tanaka, Katsunori, Chen, Xiao-Bo, Baber, Beth A., McGowan, Clare H., Russell, Paul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191557598
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