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H3K4me1 Distribution Predicts Transcription State and Poising at Promoters

Monomethylation on lysine 4 of histone H3 (H3K4me1) is commonly associated with distal enhancers, but H3K4me1 is also present at promoter regions proximal to transcription start sites. To assess a possible role for H3K4me1 in dictating gene regulatory states at promoters, we examined H3K4me1 peak de...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Bae, Sunhee, Lesch, Bluma J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214686/
https://ncbi.nlm.nih.gov/pubmed/32432110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00289
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