Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease

Lipid-based RNA nanocarriers have been recently accepted as a novel therapeutic option in humans, thus increasing the therapeutic options for patients. Tailored nanomedicines will enable to treat chronic liver disease (CLD) and end-stage liver cancer, disorders with high mortality and few treatment...

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Udgivet i:Cell Death Dis
Main Authors: Woitok, Marius Maximilian, Zoubek, Miguel Eugenio, Doleschel, Dennis, Bartneck, Matthias, Mohamed, Mohamed Ramadan, Kießling, Fabian, Lederle, Wiltrud, Trautwein, Christian, Cubero, Francisco Javier
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214425/
https://ncbi.nlm.nih.gov/pubmed/32393755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2571-4
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