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Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease
Fas Ligand (FasL) and Fas (APO-1/CD95) are members of the TNFR superfamily and may trigger apoptosis. Here, we aimed to elucidate the functional role of Fas signaling in an experimental model of chronic liver disease, the hepatocyte-specific NEMO knockout (NEMO(Δhepa)) mice. We generated NEMO(Δhepa)...
Gespeichert in:
| Veröffentlicht in: | Cell Death Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368573/ https://ncbi.nlm.nih.gov/pubmed/30737368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1391-x |
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