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Protective effects of paeoniflorin against FasL-induced apoptosis of intervertebral disc annulus fibrosus cells via Fas-FasL signalling pathway

In the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. Apoptosis is as essential as the function of proteoglycan synthesis in assessing the possible degeneration of intervertebral discs; paeoniflorin (PF) induces cytoprot...

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Vydáno v:Exp Ther Med
Hlavní autoři: CHEN, SHAO-QING, LIN, JIAN-PING, ZHENG, QI-KAI, CHEN, SHUI-JIN, LI, MING, LIN, XIAN-ZHAO, WANG, SHI-ZHONG
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665715/
https://ncbi.nlm.nih.gov/pubmed/26668640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2776
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