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Role of Fas/FasL in regulation of inflammation in vaginal tissue during HSV-2 infection

To assess the role of Fas in lesion development during genital HSV-2 infection, we used a well-established HSV-2 murine model applied to MRL-Fas(lpr)/J (Fas−/−) and C3-Fasl(gld)/J (FasL−/−) C57BL6 mice. In vitro infection of murine keratinocytes and epithelial cells was used to clarify molecular det...

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Detalhes bibliográficos
Main Authors: Krzyzowska, M, Shestakov, A, Eriksson, K, Chiodi, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101811/
https://ncbi.nlm.nih.gov/pubmed/21412278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.14
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