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Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA
Metazoan microRNAs require specific maturation steps initiated by Microprocessor, comprised of Drosha and DGCR8. Lack of structural information for the assembled complex has hindered understanding how Microprocessor recognizes primary microRNA transcripts (pri-miRNAs). Here we present a cryo-electro...
Tallennettuna:
| Julkaisussa: | Mol Cell |
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| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7214211/ https://ncbi.nlm.nih.gov/pubmed/32220646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.02.016 |
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