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Posttranscriptional Crossregulation between Drosha and DGCR8
The Drosha-DGCR8 complex, also known as Microprocessor, is essential for microRNA (miRNA) maturation. Drosha functions as the catalytic subunit, while DGCR8 (also known as Pasha) recognizes the RNA substrate. Although the action mechanism of this complex has been intensively studied, it remains uncl...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680683/ https://ncbi.nlm.nih.gov/pubmed/19135890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.10.053 |
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