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Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing
DGCR8/Pasha is an essential cofactor for Drosha, a nuclear RNase III that cleaves the local hairpin structures embedded in long primary microRNA transcripts (pri-miRNAs) in eukaryotes. Although our knowledge of pri-miRNA processing has significantly advanced in recent years, the precise role of DGCR...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636349/ https://ncbi.nlm.nih.gov/pubmed/16963499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl458 |
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