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Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis

Cleavage of microRNAs and mRNAs by Drosha and its cofactor Pasha/DGCR8 is required for animal development, but whether these proteins also have independent roles in development has been unclear. Known phenotypes associated with loss of either one of these two proteins are very similar and consistent...

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Detalhes bibliográficos
Main Authors: Luhur, Arthur, Chawla, Geetanjali, Wu, Yen-Chi, Li, Jing, Sokol, Nicholas S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910640/
https://ncbi.nlm.nih.gov/pubmed/24474768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318445111
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