Intestinal alkaline phosphatase targets the gut barrier to prevent aging

Gut barrier dysfunction and gut-derived chronic inflammation play crucial roles in human aging. The gut brush border enzyme intestinal alkaline phosphatase (IAP) functions to inhibit inflammatory mediators and also appears to be an important positive regulator of gut barrier function and microbial h...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Kühn, Florian, Adiliaghdam, Fatemeh, Cavallaro, Paul M., Hamarneh, Sulaiman R., Tsurumi, Amy, Hoda, Raza S., Munoz, Alexander R., Dhole, Yashoda, Ramirez, Juan M., Liu, Enyu, Vasan, Robin, Liu, Yang, Samarbafzadeh, Ehsan, Nunez, Rocio A., Farber, Matthew Z., Chopra, Vanita, Malo, Madhu S., Rahme, Laurence G., Hodin, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213802/
https://ncbi.nlm.nih.gov/pubmed/32213701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134049
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