Intestinal alkaline phosphatase targets the gut barrier to prevent aging

Gut barrier dysfunction and gut-derived chronic inflammation play crucial roles in human aging. The gut brush border enzyme intestinal alkaline phosphatase (IAP) functions to inhibit inflammatory mediators and also appears to be an important positive regulator of gut barrier function and microbial h...

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發表在:JCI Insight
Main Authors: Kühn, Florian, Adiliaghdam, Fatemeh, Cavallaro, Paul M., Hamarneh, Sulaiman R., Tsurumi, Amy, Hoda, Raza S., Munoz, Alexander R., Dhole, Yashoda, Ramirez, Juan M., Liu, Enyu, Vasan, Robin, Liu, Yang, Samarbafzadeh, Ehsan, Nunez, Rocio A., Farber, Matthew Z., Chopra, Vanita, Malo, Madhu S., Rahme, Laurence G., Hodin, Richard A.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2020
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213802/
https://ncbi.nlm.nih.gov/pubmed/32213701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134049
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