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Inferring the immune response from repertoire sequencing

High-throughput sequencing of B- and T-cell receptors makes it possible to track immune repertoires across time, in different tissues, and in acute and chronic diseases or in healthy individuals. However, quantitative comparison between repertoires is confounded by variability in the read count of e...

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Pubblicato in:PLoS Comput Biol
Autori principali: Puelma Touzel, Maximilian, Walczak, Aleksandra M., Mora, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213749/
https://ncbi.nlm.nih.gov/pubmed/32348312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007873
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