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repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data

Motivation: The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are composed of random events—choices of gene templates, base pair deletions and insertions—described by probability...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Elhanati, Yuval, Marcou, Quentin, Mora, Thierry, Walczak, Aleksandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920122/
https://ncbi.nlm.nih.gov/pubmed/27153709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw112
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