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repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Motivation: The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are composed of random events—choices of gene templates, base pair deletions and insertions—described by probability...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4920122/ https://ncbi.nlm.nih.gov/pubmed/27153709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw112 |
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