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Fhit and Wwox loss-associated genome instability: genome caretaker one-two punch
Expression of Fhit and Wwox protein is frequently lost or reduced in many human cancers. In this report, we provide data that further characterizes the molecular consequences of Fhit loss in the initiation of DNA double-strand breaks (DSBs), and of Wwox loss in altered repair of DSBs. We show that l...
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| Publicado en: | Adv Biol Regul |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7213024/ https://ncbi.nlm.nih.gov/pubmed/27773744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2016.09.008 |
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