Efficacy of ruthenium coordination complex–based Rutherrin in a preclinical rat glioblastoma model

BACKGROUND: Glioblastoma is an aggressive brain cancer in adults with a grave prognosis, aggressive radio and chemotherapy provide only a 15 months median survival. METHODS: We evaluated the tolerability and efficacy of the Ruthenium-based photosensitizer TLD-1433 with apo-Transferrin (Rutherrin) in...

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Библиографические подробности
Опубликовано в: :Neurooncol Adv
Главные авторы: Munegowda, Manjunatha Akathatti, Fisher, Carl, Molehuis, Daniel, Foltz, Warren, Roufaiel, Mark, Bassan, Jay, Nitz, Mark, Mandel, Arkady, Lilge, Lothar
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212850/
https://ncbi.nlm.nih.gov/pubmed/32642649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz006
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