Targeting the glucocorticoid receptor reduces binge-like drinking in High Drinking in the Dark (HDID-1) mice

BACKGROUND: Chronic alcohol exposure can alter glucocorticoid receptor (GR) function in some brain areas that promotes escalated and compulsive-like alcohol intake. GR antagonism can prevent dependence-induced escalation in drinking, but very little is known about the role of GR in regulating high-r...

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Bibliographic Details
Published in:Alcohol Clin Exp Res
Main Authors: Savarese, Antonia M., Ozburn, Angela R., Metten, Pamela, Schlumbohm, Jason P., Hack, Wyatt R., LeMoine, Kathryn, Hunt, Hazel, Hausch, Felix, Bauder, Michael, Crabbe, John C.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211124/
https://ncbi.nlm.nih.gov/pubmed/32154593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14318
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