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Targeting the glucocorticoid receptor reduces binge-like drinking in High Drinking in the Dark (HDID-1) mice

BACKGROUND: Chronic alcohol exposure can alter glucocorticoid receptor (GR) function in some brain areas that promotes escalated and compulsive-like alcohol intake. GR antagonism can prevent dependence-induced escalation in drinking, but very little is known about the role of GR in regulating high-r...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Savarese, Antonia M., Ozburn, Angela R., Metten, Pamela, Schlumbohm, Jason P., Hack, Wyatt R., LeMoine, Kathryn, Hunt, Hazel, Hausch, Felix, Bauder, Michael, Crabbe, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211124/
https://ncbi.nlm.nih.gov/pubmed/32154593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14318
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