Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes

We report the topical administration of sponge Haliclona sp. Spicules (SHS) combined with cationic flexible liposomes (CFL) to increase the delivery of small interfering RNA (siRNA) into viable skin cells in vitro and in vivo. SHS can be applied topically as novel microneedles to overcome skin barri...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther Nucleic Acids
Asıl Yazarlar: Liang, XueJiao, Zhang, JiaLiang, Ou, HuiLong, Chen, Jun, Mitragotri, Samir, Chen, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210381/
https://ncbi.nlm.nih.gov/pubmed/32380414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.04.003
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