Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

The prefusion conformation of HIV-1 envelope protein (Env) is recognized by most broadly neutralizing antibodies (bnAbs). Studies showed that alterations of its membrane-related components, including the transmembrane domain (TMD) and cytoplasmic tail (CT), can reshape the antigenic structure of the...

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Udgivet i:Nat Commun
Main Authors: Piai, Alessandro, Fu, Qingshan, Cai, Yongfei, Ghantous, Fadi, Xiao, Tianshu, Shaik, Md Munan, Peng, Hanqin, Rits-Volloch, Sophia, Chen, Wen, Seaman, Michael S., Chen, Bing, Chou, James J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210310/
https://ncbi.nlm.nih.gov/pubmed/32385256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16165-0
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