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Structural Basis for Membrane Anchoring of HIV-1 Envelope Spike
HIV-1 envelope spike (Env) is a type I membrane protein that mediates viral entry. We use NMR to determine an atomic structure of the transmembrane (TM) domain of HIV-1 Env reconstituted in bicelles that mimic a lipid bilayer. The TM forms a well-ordered trimer that protects a conserved membrane-emb...
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| Gepubliceerd in: | Science |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5085267/ https://ncbi.nlm.nih.gov/pubmed/27338706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7066 |
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