Structure of the membrane proximal external region of HIV-1 envelope glycoprotein

The membrane-proximal external region (MPER) of the HIV-1 envelope glycoprotein (Env) bears epitopes of broadly neutralizing antibodies (bnAbs) from infected individuals; it is thus a potential vaccine target. We report an NMR structure of the MPER and its adjacent transmembrane domain in bicelles t...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Fu, Qingshan, Shaik, Md Munan, Cai, Yongfei, Ghantous, Fadi, Piai, Alessandro, Peng, Hanqin, Rits-Volloch, Sophia, Liu, Zhijun, Harrison, Stephen C., Seaman, Michael S., Chen, Bing, Chou, James J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156635/
https://ncbi.nlm.nih.gov/pubmed/30185554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807259115
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