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Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein
A major goal for HIV-1 vaccine development is the production of an immunogen to mimic native, functional HIV-1 envelope trimeric spikes (Env) on the virion surface. We lack a reliable description of a native, functional trimer, however, because of inherent instability and heterogeneity in most prepa...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701381/ https://ncbi.nlm.nih.gov/pubmed/26113642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa9804 |
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