Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein

A major goal for HIV-1 vaccine development is the production of an immunogen to mimic native, functional HIV-1 envelope trimeric spikes (Env) on the virion surface. We lack a reliable description of a native, functional trimer, however, because of inherent instability and heterogeneity in most prepa...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Chen, Jia, Kovacs, James M., Peng, Hanqin, Rits-Volloch, Sophia, Lu, Jianming, Park, Donghyun, Zablowsky, Elise, Seaman, Michael S., Chen, Bing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701381/
https://ncbi.nlm.nih.gov/pubmed/26113642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa9804
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