MON-714 CRISPR / Cas9 Genomic Edition of the CDH2 Gene in Zebrafish Leads to Eye and Cardiac Malformation

Introduction: The CDH2 gene encodes a transmembrane protein responsible for calcium-dependent cell-cell adhesion that participates in the process of embrionic development. Neural development is achieved by neuronal neurulation, migration and differentiation, as well as axon growth and synapse format...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Ventura, Bianca Helena, Bissegatto, Débora Delmonte, Arnhold, Ivo J, Carvalho, Luciani Renata Silveira
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Genetics and Development (including Gene Regulation)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207347/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1674
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