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The Myosin Duty Ratio Tunes the Calcium Sensitivity and Cooperative Activation of the Thin Filament
In striated muscle, calcium binding to the thin filament (TF) regulatory complex activates actin–myosin ATPase activity, and actin–myosin kinetics in turn regulates TF activation. However, a quantitative description of the effects of actin–myosin kinetics on the calcium sensitivity (pCa(50)) and coo...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7207222/ https://ncbi.nlm.nih.gov/pubmed/23947752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400262h |
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