The Myosin Duty Ratio Tunes the Calcium Sensitivity and Cooperative Activation of the Thin Filament

In striated muscle, calcium binding to the thin filament (TF) regulatory complex activates actin–myosin ATPase activity, and actin–myosin kinetics in turn regulates TF activation. However, a quantitative description of the effects of actin–myosin kinetics on the calcium sensitivity (pCa(50)) and coo...

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Bibliografiska uppgifter
I publikationen:Biochemistry
Huvudupphovsmän: Webb, Milad, Jackson, Del R., Stewart, Travis J., Dugan, Samuel P., Carter, Michael S., Cremo, Christine R., Baker, Josh E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207222/
https://ncbi.nlm.nih.gov/pubmed/23947752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400262h
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