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Using Fluorescent Myosin to Directly Visualize Cooperative Activation of Thin Filaments

Contraction of striated muscle is tightly regulated by the release and sequestration of calcium within myocytes. At the molecular level, calcium modulates myosin's access to the thin filament. Once bound, myosin is hypothesized to potentiate the binding of further myosins. Here, we directly ima...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Desai, Rama, Geeves, Michael A., Kad, Neil M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303648/
https://ncbi.nlm.nih.gov/pubmed/25429108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.609743
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