Tunable Enzymatic Synthesis of the Immunomodulator Lipid IV(A) To Enable Structure–Activity Analysis

The Lipid A family of glycolipids, found in the outer membranes of all Gram-negative bacteria, exhibits considerable structural diversity in both lipid and glycan moieties. The lack of facile methods to prepare analogues of these natural products represents a major roadblock in understanding the rel...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Sankaranarayanan, Karthik, Antaris, Xirui X., Palanski, Brad A., El Gamal, Abrahim, Kao, Camilla M., Fitch, William L., Fischer, Curt R., Khosla, Chaitan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206895/
https://ncbi.nlm.nih.gov/pubmed/31184877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b03066
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