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In Vivo Measurement of Redox-Regulated TG2 Activity

Transglutaminase 2 (TG2) is a ubiquitous mammalian enzyme that is implicated in a variety of physiological processes and human diseases. Normally, extracellular TG2 is catalytically dormant due to formation of an allosteric disulfide bond between Cys370–371 of the enzyme. In this protocol, we descri...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Melkonian, Arek V., Weng, Nielson, Palanski, Brad A., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852785/
https://ncbi.nlm.nih.gov/pubmed/31069776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9187-7_16
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