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Tunable Enzymatic Synthesis of the Immunomodulator Lipid IV(A) To Enable Structure–Activity Analysis
The Lipid A family of glycolipids, found in the outer membranes of all Gram-negative bacteria, exhibits considerable structural diversity in both lipid and glycan moieties. The lack of facile methods to prepare analogues of these natural products represents a major roadblock in understanding the rel...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206895/ https://ncbi.nlm.nih.gov/pubmed/31184877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b03066 |
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