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Dietary phytate lowers K-ras mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer

OBJECTIVE(S): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions. The present study was designed to determine whether dietary phytate affects mutation frequency in colon epithelial cells challenged with azoxymethane in vivo, through lowering the formation of...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Pallem, Poorna Venkata Satya Prasad, Bodiga, Sreedhar, Bodiga, Vijaya Lakshmi
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206830/
https://ncbi.nlm.nih.gov/pubmed/32405345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2019.34374.8161
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