TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin

Metastasis is one of the main contributors to the poor prognosis of hepatocellular carcinoma (HCC). However, the underlying mechanism of HCC metastasis remains largely unknown. Here, we showed that TXNDC12, a thioredoxin-like protein, was upregulated in highly metastatic HCC cell lines as well as in...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Yuan, Kefei, Xie, Kunlin, Lan, Tian, Xu, Lin, Chen, Xiangzheng, Li, Xuefeng, Liao, Mingheng, Li, Jiaxin, Huang, Jiwei, Zeng, Yong, Wu, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206186/
https://ncbi.nlm.nih.gov/pubmed/31570854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0421-7
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