KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3

BACKGROUND: N6-methyladenosine (m6A) modification, the most abundant internal methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the largest known component in the m6A methyltransferase complex, KIAA1429 plays a vital role in m6A methylation. However, its funct...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Lan, Tian, Li, Hui, Zhang, Delin, Xu, Lin, Liu, Hailing, Hao, Xiangyong, Yan, Xiaokai, Liao, Haotian, Chen, Xiangzheng, Xie, Kunlin, Li, Jiaxin, Liao, Mingheng, Huang, Jiwei, Yuan, Kefei, Zeng, Yong, Wu, Hong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921542/
https://ncbi.nlm.nih.gov/pubmed/31856849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1106-z
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