OX40 expression in hepatocellular carcinoma is associated with a distinct immune microenvironment, specific mutation signature, and poor prognosis

Immunotherapy's effect against hepatocellular carcinoma (HCC) is hampered by immunosuppressive mechanisms in the tumor microenvironment. We assessed the clinicopathologic and biologic relevance of OX40, a costimulatory molecular expressed by regulatory T cells (Tregs), in HCC. We analyzed the i...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Xie, Kunlin, Xu, Lin, Wu, Hao, Liao, Haotian, Luo, Lin, Liao, Mingheng, Gong, Jianping, Deng, Yang, Yuan, Kefei, Wu, Hong, Zeng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889283/
https://ncbi.nlm.nih.gov/pubmed/29632718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1404214
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