OX40 expression in hepatocellular carcinoma is associated with a distinct immune microenvironment, specific mutation signature, and poor prognosis

Immunotherapy's effect against hepatocellular carcinoma (HCC) is hampered by immunosuppressive mechanisms in the tumor microenvironment. We assessed the clinicopathologic and biologic relevance of OX40, a costimulatory molecular expressed by regulatory T cells (Tregs), in HCC. We analyzed the i...

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Publicado en:Oncoimmunology
Autores principales: Xie, Kunlin, Xu, Lin, Wu, Hao, Liao, Haotian, Luo, Lin, Liao, Mingheng, Gong, Jianping, Deng, Yang, Yuan, Kefei, Wu, Hong, Zeng, Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889283/
https://ncbi.nlm.nih.gov/pubmed/29632718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1404214
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